Afghanis-tan illustrates the modern history of Afghanistan and its neighboring countries, starting from the imperialist era in the 19th century, through moe anthropomorphism. The title character, a short and clumsy bishōjo, is a national personification of Afghanistan. Other female characters personify the nearby nations of Central Asia, such as Pakistan and Uzbekistan. Nations that have fought wars in Afghanistan at various times, such as Britain, the Soviet Union and the United States also make appearances. The Taliban government and Al-Qaeda terrorist group are also represented in the comic.