Osanai Kirihito, a medical doctor at a large university hospital, tries to find out the cause of Monmou Disease, which changes a human body into that of a dog. However, he is involved in a power game in the hospital and caught the disease.

En uno de los mejores hospitales universitarios de Japón, un médico que aspira a ser el dirigente del consejo general estudia el mal de Monmo, una enfermedad que produce un cambio en los huesos, acorta las extremidades y transforma el hombre en una especie de perro. Kirihito, un miembro de su equipo, no está de acuerdo con su tesis de contagio y viaja al pueblo donde en principio se desarrolla la enfermedad de forma exclusiva. En su afán de demostrar que su mentor está equivocado, se verá afectado por la enfermedad y se relacionará con una serie de personajes que aparecerán en varias ocasiones y que sirven de hilo conductor de a historia. Por otro lado, Urabe, un amigo suyo también doctor con un temperamento algo desequilibrado, intentará ayudarle desde Japón, aunque a veces no de la forma más ortodoxa.

外国の小さな村にいた桐人は、竜ヶ浦教授の裏切りを知った!急ぎ帰国した桐人は、今や野望をとげ、日本医師会会長の座を手に入れた竜ヶ浦に復讐を誓うのだった!感動の大河ヒューマン・ドラマ、堂々の完結編!! 【目次】 閃光 幻のマリア 帰郷 邂逅（1） 邂逅（2） カタストロフィ プログノーシス

It may or may not be contagious. There seems to be no cure for it. Yet, Monmow Disease, a life-threatening condition that transforms a person into a dog-like beast, is not the only villain in this shocking triumph of a medical thriller by manga-god Osamu Tezuka. Said to have been the personal favorite of the artist, who held a degree in medicine, and surprisingly attentive to Christian themes and imagery, Ode to Kirihito demolishes naive notions about human nature and health and likely preconceptions about the comics master himself. From pregnant vistas of the Japanese countryside to closed rooms full of sin and redemption, Tezuka astounds for more than eight hundred continuous pages, his art in turn easefully concise and flamboyantly experimental, his inquiry into our most repugnant instincts and prospects for overcoming them unflinchingly serious. Incorporating elements of the often lurid and adult-oriented “gekiga” style for the first time, Tezuka entered into his fruitful late period with this work. A promising young doctor, Kirihito Osanai visits a remote Japanese mountain village to investigate the source of the latest medical mystery. While he ends up traveling the world to discover what it takes to be cured of such a disease, a conspiracy back home attempts to explain away his absence. Hinging upon his fate are those of his loved an unstable childhood friend and colleague trapped between factions of the medical establishment that nurtured him; a fiancée emotionally transformed by Kirihito’s mysterious disappearance; and a stranger who becomes his guardian angel, a sensual circus-act performer with volatile psychological secrets. From plutocratic Taipei and racially divided South Africa to backwater Arabia and modern Osaka, ambition and desire beckon “normal men” to behave uglier than any beast. Riveting our attention on deformity and its acceptance like The Elephant Man by David Lynch, Ode to Kirihito examines the true worth of human beings through and beyond appearances.