THE RETURN OF A CLASSIC SYMBIOTE…AND IT’LL BE A SCREAM! Years ago, Patricia Robertson was unwillingly bonded to the clone of Venom that eventually became Mania, and she’s been living in fear of symbiotes ever since. But she’s also been living with a secret, and with the coming of Carnage, Patricia must take a stand—and will have no choice but to confront her demons head-on!

Patricia Robertson may know symbiotes…but nothing could have ever prepared her for their god, KNULL! With Carnage building strength to call the symbiote god to Earth, Patricia must harness the power of the Scream symbiote! Can Scream withstand the draw of Knull, or are they doomed to be another casualty?

Between Knull’s growing psychic influence and Patricia Robertson serving as its host, the Scream symbiote is being psychologically torn apart!But there’s no time for weakness as Cletus Kasady unleashes an onslaught of infected inmates on an unsuspecting New York. Scream and Carnage may be symbiotic siblings, but that won’t stop ‘em from SLAUGHTERING one another!