Detective Mario DeLuca and his new partner search for justice in an unconventional manner throughout the city of New Orleans. Mario, a close friend to many criminals but still high in the ranks of law enforcement, has imprisoned several dangerous individuals, including Felipe Cruz. After vowing revenge in court, Felipe presides over the streets of New Orleans from jail, and he soon makes good on his promise by trying to harm Mario's fiancé, Kate Fontenot. In the second installment of Vito Zuppardo's True Blue Detective series, Dr. Walter Ross' black market organ enterprise is dismantled after another mysterious death at Riverside Inn. Retired detective Zack Nelson and their mysterious chauffeur Howard join together with Mario to capture Felipe and the Cornerview Gang following a failed abduction attempt on Kate Fontenot. Tired of failing to uphold justice within the legal system, Mario takes matters into his own hands by utilizing an untraditional approach to battling crime; with Howard and Zack's assistance they overthrow Felipe and his henchmen in a way that was completely unexpected. Crescent City Detective transports readers on a thrilling journey through the alleys of New Orleans full of mystery, romance, and misfortune.