Exotic veterinarian Dr. Sterling Mead and his wife, embryologist Dr. Tonya Mead are accustomed to danger once escaping a volcano eruption, becoming stranded in the Canadian wilderness after a helicopter crash and later surviving an avalanche which almost destroyed the North Star Weather Station. Now that all of that is behind them, Sterling and Tonya can devote their time without interruptions to their research with the help of their friends and Finn’s Paranthropus tribe, overseeing and protecting the multitude of prehistoric mammals the couple have created that are thriving in an undisclosed desolate region of the Yukon Territory. But that is all about to change when ruthless trappers happen upon the remote animal preserve unbeknownst to the outside world and creatures long believed to be extinct are caught up in the crosshairs.