JONATHAN HICKMAN RE-INVENTS THE COSMOLOGY OF THE MARVEL UNIVERSE! WHAT HAPPENS WHEN THE-POWERS-THAT-BE MEET THE-NATURAL-ORDER-OF-THINGS? The infinite détente between THE-NATURAL-ORDER-OF-THINGS and THE-POWERS-THAT-BE nears an end. Old acquaintances are reunited during a Babylon Event. The Lion of Wolves throws the worst parties. Don't look under the table. There's a John Wilkes Booth penny on the ground. This ENORMOUS EXTRA-SIZED first issue features DOCTOR STRANGE, who, while not boring at all, is easily the most boring person in the book.

Jonathan Hickman & Valerio Schiti continue to redefine the Marvel Cosmology! The Centum normally has twenty-five Primes, now only three remain. College isn't worth the time or the money. There's a hidden book in the hidden library that hides a hidden door. Kubisk Core is from Georgia, like that matters.

Cassandra is cursed with knowing the future, but no one believes her. There are Black Swans in the bar. Oblivion wants to drink alone, but kids these days don't respect authority figures. Most of the ingredients are illegal outside of Hell's Kitchen.

That guy in the beekeeper suit is holding a thing that's freaking everyone out. A Skinner box is bigger on the inside than the outside. The Avatar makes an enemy on the Axis of Power. If you save the universe and no one remembers, is it worth it? Maybe.

The clinic has a wall covered in words. They are written in the blood of men, but no one can read them. Mia gets her first apartment. The juice isn't worth the squeeze.

Aiko has done a bad thing, and the only way she can set it right is to tell the truth and stop lying. But who doesn't love lying? Certainly not the Lion of Wolves.

Dimitri is an orphan who was born in the Cosmodrome. Out there somewhere is what he's been looking for his whole life. The way in is the way through. All you have to do is listen for the signal.

If you could go back and erase the biggest mistake you've ever made, would you? Of course you would. So let's do that. And let the pieces fall where they may.