After so much uncertainty, the hospital’s operating budget has officially reached the breaking point, and layoffs are imminent. James Bell, having recently ceded his seniority for a position in the new Holistic Cardiac wing, could be one of the unlucky ones. James can’t help questioning God’s plan for him, before receiving an important reminder from the unlikeliest of places that God have very special plans for him. As a supervisor, Anabelle Scott is charged with laying off some good friends. The difficult task leads her to seriously contemplate retirement to spare a younger nurse’s job. Amidst the news, a jittery Heath tells Candace Crenshaw that they need to talk. What could it be about? Meanwhile, Elena Rodriguez’s granddaughter Isabel is struggling with her reading and may be held back as a result. Isabel’s parents, the constantly-at-odds Raphael and Sarah, end up rallying in a truly inspirational way for the benefit of their daughter. At the hospital, a man who drink himself into a stupor denies he has a problem. What can the nurses do to help him realize there’s a better path, that God’s love can guide him through life’s trials?

With Candace and Heath’s wedding fast approaching, Anabelle Scott decides to make a beautiful double-ring quilt as their gift. Planning and buying fabric serves as a good distraction from meddling in the lives of her children—particularly in her son Evan’s, who recently began dating a woman with children. Anabelle prays for guidance as she comes to terms with what it means to be a family and accepts her own family’s future with open arms. Meanwhile, Candace Crenshaw and Heath Carlson are in the home-stretch. Are Heath’s jittery nerves normal or do they signify something else? Elena Rodriguez thinks her son Rafael doth protest too much when it comes to his feelings for his ex-girlfriend Sarah. The situation is bound to get complicated now that Sarah may be dating someone new. When James Bell is hospitalized with a terrible infection, the Bell household falls into disarray. James’s friends end up rallying to get his harried family back on track. At the hospital, the new chaplain often speaks to the incredible power of prayer, and now Anabelle’s patient firmly believes that if she prays hard enough, she will be healed. How can Anabelle show the woman that the answers aren’t always that simple? That God works in wondrous ways we don’t always understand?

Elena Rodriguez is excited to oversee the Hospital committee organizing several community fund-raisers for cancer research - which is why she's stunned to receive alarming information about her own health. The work she's doing takes on new and profound meaning as she confronts her decisions she never imagined she'd have to make. As Elena copes with her news, James Bell and his wife Fern celebrate their own: Fern's MS is in remission! After Nine years of uncertainty, Fern can't wait to start living life to the fullest again, if only James would let her. He can't help worrying his wife is overexerting herself. Meanwhile, newlyweds Candace and Heath Carlson begin to learn about each other's quirks. How can Candace accept it's no longer her house, but theirs? Annabelle Scott and her husband Cam are proud of their hardworking son Evan as he plans an autumn maze and pumpkin patch at the family business. It's the perfect way to celebrate the season, until an unexpected disaster puts the business' future in doubt. At the hospital's Walk for a Cure, Elena sees her granddaughter Izzy enthusiastically supporting her Buela. She's reminded that is is not alone in her fight - that she, her family, her friends, and community are in this together

When a blizzard hits Deerford, James Bell vows to do whatever it takes to save a patient’s life, even travel the treacherous roads to retrieve an organ for a transplant. Word begins to spread that he’s a shoo-in for an upcoming promotion—that is, until he learns he’s vying against a less experienced candidate who has connections on the board. Is it a lost cause? Anabelle Scott doesn’t cope well with change, and there’s a great deal of it going on in her life. She decides it’s the right time to retire, but being retired turns out to be much more difficult than she imagined. What does God want her to do? Meanwhile, Candace Carlson wakes up feeling sick and she vows to take it easier, until a niggling thought enters her mind—could it be possible that she and Heath are about to expand their family? With Elena Rodriguez’s ongoing health concerns, she reflects on how precious time is. It’s finally time to take her dream trip to Spain. And when will her son Rafael finally confront his feelings for Sarah? Their daughter Izzy is growing up so fast, and it’s time the three of them became the family they were always meant to be. It’s the perfect time for new beginnings.