When Cindy Winters' sister, Heidi, is seriously injured, Cindy and her classmate, Veronica, make friends with Tina Wu, a girl with lupus, and the other patients in the pediatric wing at Hope Hospital

Krystal, who thinks looks are everything, learns a valuable lesson from eight-year old Marissa who is undergoing a series of operations to reconstruct her face following an accident.

Feeling unnoticed by her divorced parents and hoping to belong somewhere, Veronica accepts a dangerous dare to prove she is worthy of membership in the Gold Girl club