At the heart of this vibrant saga is a vast ship, the Ibis. Her destiny is a tumultuous voyage across the Indian Ocean shortly before the outbreak of the Opium Wars in China. In a time of colonial upheaval, fate has thrown together a diverse cast of Indians and Westerners on board, from a bankrupt raja to a widowed tribeswoman, from a mulatto American freedman to a free-spirited French orphan. As their old family ties are washed away, they, like their historical counterparts, come to view themselves as jahaj-bhais, or ship-brothers. The vast sweep of this historical adventure spans the lush poppy fields of the Ganges, the rolling high seas, and the exotic backstreets of Canton.

In September 1838, a storm blows up on the Indian Ocean and the Ibis, a ship carrying a consignment of convicts and indentured laborers from Calcutta to Mauritius, is caught up in the whirlwind. River of Smoke follows its storm-tossed characters to the crowded harbors of China. There, despite efforts of the emperor to stop them, ships from Europe and India exchange their cargoes of opium for boxes tea, silk, porcelain and silver. Among them are Bahram Modi, a wealthy Parsi opium merchant out of Bombay, his estranged half-Chinese son Ah Fatt, the orphaned Paulette and a motley collection of others whose pursuit of romance, riches and a legendary rare flower have thrown together. All struggle to cope with their losses—and for some, unimaginable freedoms—in the alleys and crowded waterways of 19th-century Canton.

It is 1839 and tension has been rapidly mounting between China and British India following the crackdown on opium smuggling by Beijing. With no resolution in sight, the colonial government declares war. One of the vessels requisitioned for the attack, the Hind, travels eastwards from Bengal to China, sailing into the midst of the First Opium War. The turbulent voyage brings together a diverse group of travellers, each with their own agenda to pursue. Among them is Kesri Singh, a sepoy in the East India Company who leads a company of Indian sepoys; Zachary Reid, an impoverished young sailor searching for his lost love, and Shireen Modi, a determined widow en route to China to reclaim her opium-trader husband's wealth and reputation. Flood of Fire follows a varied cast of characters from India to China, through the outbreak of the First Opium War and China's devastating defeat, to Britain's seizure of Hong Kong.