Add a little bit of Spidey and a touch of Deadpool, take away the Y chromosomes, blend it all together, and what do you get? Peter Parker and Wade Wilson's worst nightmare: the murderous, mixed-up miss named Itsy Bitsy! The “daughter” of our two heroes is stronger than them, faster than them and has seriously creepy daddy issues – but what crazed mind could have conceived of her in the first place? As the body count rises, Spider-Man and Deadpool must work together to take down Itsy Bitsy! By Joe Kelly and Ed McGuinness. Reprinting Spider-Man/Deadpool #9-10, #13-14 & #17-18.