Acre, 1291. The last Crusader city in the Holy Land is about to fall. Two Knights Templar, obeying the grandmaster’s orders, manage to escape the invading Muslim army on the order’s last ship. New York City, nowadays. During the unveiling of an exhibition of some of the Vatican’s treasures, four men disguised as Templars attack the Metropolitan Museum and steal several artefacts, including a centuries-old decoder – a loss that horrifies the Church.

Reilly has tracked down the fake Professor Sharafi to Turkey. But the man is crafty, and not only does he manage to escape, he also recaptures Tess along the way. A chase begins across the hills of Cappadocia, with the FBI agent hunting down his enemy while Tess, in order to survive, does her best to follow the trail of Knight Templar Conrad and the mysterious treasure he was protecting - the one everyone thought was a threat to all of Christianity...