Luke Cage is reunited with his old lover, but their reunion is bittersweet as she has been horribly disfigured. Luke is finally starting to put all the pieces together, and when he does—blood will run through the streets of Harlem.

Luke Cage has been set up and now he's going to settle the score. Luke finally learns the truth about Stryker, Tombstone, Officer Rachman, and the mysterious man that has been yanking his chain this whole time, from right under his nose.

A lot can change in ten years. And rarely for the better. Local legend, Luke Cage, invincible, unstoppable, unflappable, finds that out the hard way when he returns to the mean streets of Prohibition-era Harlem after a ten-year stretch in Riker's Island. All he wants is to be back in the loving arms of his woman, but certain powerful men have different plans for Cage. Willis Stryker, Cage's childhood friend turned Godfather of Harlem, wants him on his crew, and under his thumb. And wealthy white socialite Randall Banticoff, whose wife is now very dead, murdered in a Harlem alley, wants Cage to investigate her death. Cage is about to learn that coming home is never easy, and to survive he might just have to kill a whole lot of people. Collects Luke Cage Noir #1-4.