Prudence Lynch’s beloved grandmother trained her in midwifery and in folk medicine. Always ostracized because they were different—until someone needed their help—they lived in poverty at the edge of a tiny Virginia village where rumors plagued them. After Granny’s death, Prudence leaves for Richmond. There, Prudence is fortunate to be chosen to accompany Lydia Harrison to Tarnation, Texas. She believes she’s left trouble and gossip behind to establish her healing business and begin a new life. Doctor Riley Gaston wants a wife and children. He’s threatened to move from Tarnation to seek a wife, but he would never actually leave the community he loves. One of the young women Lydia brings home mesmerizes Riley. That is, until he learns her so-called profession is folk healing, which is he views as dangerous as it is worthless. Prudence is as stubborn as Riley. Trouble causes them to reconsider their opinions. Is their change of heart too late?