After a mysterious encounter in her childhood, Sakura Mamiya gained the power to see ghosts. Now a teenager, she just wishes the ghosts would leave her alone! Then one day she meets Rinne Rokudo, a boy who is far more than what he seems. While suffering from a cold, Rinne gets a visit from a very strange doctor. The surprise house call leads Rinne, Sakura and Tsubasa to a confrontation with Sabato, Rinne's deadbeat father and president of the evil Damashigami Company! The stage is set for an all-out father-son battle in the afterlife.