Michael Angel is the oldest of five brothers all of whom are unmarried, a fact which displeases their mother immensely. Susan Angel is a determined mother who chooses her eldest son as the starting point of her quest to see her children wed. However, when he falls for the wrong girl, an artistic free spirit that enraptures his soul, the family begins to fall from the control of the matriarch. Melanie Price is certainly not Mrs. Angel's first choice for her professional and upstanding son, Michael. And while she attempts to separate the lovers, her boys will all begin to fall under the spell of the little energetic and fun loving pipsqueak that has entered their lives. From the hardened construction worker, to the brooding EMT, the widower, and the emotionally scarred, the Angel boys will begin to see in Melanie a hope that perhaps having a woman in your life is something to be desired.

Brian Angel is the second oldest of the Angel boys and a man unto himself. His rough exterior is complimented with tattoos, tanned muscles, and a tendency to swear a little too often. When Georgia Allen enters his life, she matches him trait for trait and blow for blow. And when these two meet, its not sparks that fly, but her right hook across his left temple.

Nathan Angel has been mourning his wife for three years. During that time he has upheld his responsibilities and honored his wife's memory by raising their children. However, that honor has come with a price that tears at Nathan's soul. He is a good man, made that way through tragedy. In a similar fashion, Jessica Kearns has suffered heartbreak of her own. When these two meet, it will take the help of loved ones to guide them towards a mutual healing. And as they begin to heal, they will reveal their souls, and slowly the weeping will end.

Joshua Angel has been badly hurt from a previous marriage to an unscrupulous woman. Now that his brothers are getting married and finding love interests of their own, Joshua has begun a journey of healing. With the help of Melanie Angel, his new sister-in-law, as well as the rest of his caring family, Joshua will move forward and brave his emotional turmoil regarding women. His relationship with Meredith Stanton, a woman several years his senior, will allow him to laugh, hope, and aspire. When that relationship begins to sour, the Angels will be there for him. Together, they will attempt to tame his anger.

David Angel is an intense and brooding man, made that way by his very nature. Paula lane is a vibrant and caring woman, saddened due to life's circumstances. Together, they make do while trying to learn how and why the other survives. It's a mystery they will explore together, drawing on each other's strengths in the process and performing as any lover should—performing as any Guardian Angel would.

Anne Angel is a successful and resourceful businesswoman. When her father asks her to recruit Andrew Christenson for their company, she readily agrees, unaware of the impact he will have on her life. Into this mix comes Melanie Angel, who quickly becomes intent on seeing Anne and Andrew together. And with a kind heart, and a willing partner, Melanie begins the arduous task of Seducing Anne Angel.