The Scarlet Spider must face a part of him he had hoped that he left behind. With a bounty on his head, The Assassins Guild has come for Scarlet Spider. Will the murderers be caught in Kaine's web, or will the Scarlet Spider finally be squished?

Mysteries come to light as a threat from Mexico comes for Aracely. An old Spider-Man foe returns, and he's not alone. Plus: What is the secret of Kaine's new powers?

Scarlet Spider and his friends deal with the fallout from a shocking fatality. The Lobos are on the prowl as Aracely fights for her life. And who is the Other?

Spinning out of Spider-Island, The secrets of the Brand New Scarlet Spider revealed! Who is the new webbed wonder - and why has he come to face corruption in Houston, Texas? Collecting: Scarlet Spider 1-6 & material from Marvel Point One.1

Something terrible is happening in the Gulf of Mexico. When Houston-based mega-corporation ROXXON is attacked after making an astonishing discovery, Scarlet Spider finds himself right in the middle of it...defending ROXXON?!? And when the Southwest's greatest heroes, the Rangers, arrive to take down the Scarlet Spider, our webbed hero goes from Houston's newest hero to Houston's most wanted. But as the mystery deepens, both sides learn what the corporation's greed has brought down upon Houston. Mammon has been unleashed, and Scarlet Spider and the Rangers have no hope of stopping it! Plus: a door has been opened at NASA's Houston facility - and Scarlet Spider's life will never be the same. It's a bold new era of web-spinning excitement in the Mighty Marvel Manner! Collecting: Scarlet Spider 7-9, 12.1, 12-15

In the wake of the Superior Spider-Man's dubious public actions, the world has learned to fear the Spiders. And when terrorists attack one of Houston's most famous landmarks, Kaine's ready to put that fear to use! Then: it's the showdown of the century, as the Scarlet Spider takes on Wolverine! Kaine owes a fatal favor to the Assassins Guild: one murder, no questions asked. And guess who they want dead? Hint: SNIKT! Guest starring the X-Men! Chris Yost, Khoi Pham and Carlo Barberi continue the adrenaline-packed adventures of the world's most dangerous super hero! Collecting: Scarlet Spider 16-20 & Superior Spider-Man Team-Up 2

After the last volume's shocking ending, everything has changed for Kaine. His second chance at life is over. At his lowest point, he comes face to face with the one man that's fueled his obsession, hate and guilt his enti re life...Ben Reilly, the original Scarlet Spider. Alone, adrift, beaten and lost, Kaine's hard-fought and hard-won life has been ripped apart piece by piece. His body is broken. And his soul is next. Enter the Hunter. Collecting: Scarlet Spider 21-25