Follows the adventures of May "Mayday" Parker, Spider-Man's daughter, who inherits her father's special abilities and battles numerous villains, including Mr. Nobody, Kaine, and the Green Goblin.

Her name is May Mayday Parker, and she recently learned her father was the original Spider-Man. The good news is that she's having the time of her life as she hones the amazing spider-like abilities she inherited from him. The bad news is that some of her roughest battles lie ahead - against the likes of Ladyhawk, the Kingpin of Crime, Mr. Nobody, Crazy Eight...and her won parents?!

The adventures of Spider-Man's daughter continue as Mayday Parker faces defeat and disgrace at the hands of Darkdevil, the Avengers, and Kaine! Beset by problems in her civilian guise, Spider-Girl teams up with Speedball to take on Mr. Abnormal! Collects Spider-Girl issues #12-16, Spider-Girl 1999 Annual.

Sworn to follow in her father's web tracks, May "Mayday" Parker's got a lot on her plate - but an upstart imitator wants to help himself to her heritage! Who is the new Spider-Man and what role will he play in Spider-Girl's reality? Guest-starring the Avengers of A-Next - with looks into the legacies of the FF, the X-Men and the New Warriors! Collects Spider-Girl #28-33.

Who will lead the New York underworld? Will the Green Goblin go good or give grief? What secret is Mary Jane keeping? And who is the NEXT true Spider-Man? Guest-starring the Fantastic Five Collects Spider-Girl #34-38, 51.

Wall-crawling gets crowded when a new Spider-Man and Scarlet Spider swing into action, and the one true web-slinger joins Spider-Girl to clear up the costumed clonery Plus: One of Spider-Girl's longtime foes meets his doom, prompting his family into vengeful action And introducing the MC-2 incarnation of the New Warriors Collects Spider-Girl #39-44

The new Scarlet Spider debuts, and the one true Spider-Man returns - but can even three web-slingers defeat the awesome Apox the Omega Skrull? Angel Face and Funny-Face are on the loose, leaving Spider-Girl to face up to her quarrels with the New Warriors before the final faceoff Plus: startling secrets of Mayday's past and a confrontation with everyone's favorite cantankerous clone, Kaine Guest-starring the Fantastic Five and Avengers Next Collects Spider-Girl #45-50.

May Parker has battled the Soldiers of the Serpent before and come out ahead. But this time, they have united behind an enigmatic, powerful leader, and May's spider powers might not be enough to save her this time. Also, May's romantic life takes a sudden left turn. Plus, the return of the Scarlet Spider Collects Spider-Girl #52-59.

There's a new gang war in New York City, but what's a gang war without a Parker caught in the middle? The rivalry between the Kingpin and challenger Canis has heated up, and even Spider-Girl can't end it before the death of a classic Marvel villain Meanwhile, more villains pop up guided by a mysterious agenda To them, Spider-Girl's just a troublemaker - but the Black Tarantula thinks she's destined for more... and for him Plus, crises at Midtown High Guest-starring Darkdevil and Kaine the corrupted clone Collects Spider-Girl #60-66.

Mayday faces mutants, magic, and more! Spider-Girl battles old enemies and new, alongside her era's New Warriors and alone, while a mysterious figure plans his own web of intrigue around her! Featuring J2, Raptor, and other Spider-Girl super-peers! Collects Spider-Girl #67-72.