While a deadly virus races through the world’s population, survivors struggle to find others who are still alive because nobody wants to be Alone at the End of the World. Thirteen-year-old Ethan should be practicing his skateboard moves, not watching his family members die, one by one. He knows he could become a victim of the evil infection at any minute. Scared and alone, he fills his backpack and goes in search of other survivors, hoping he lives long enough to find someone. Anyone. When Cassie sees the bodies of neighbors and strangers littering what had been pristine front lawns, she realizes her intense focus on business and family may have saved their lives. How does a single mom and her two kids survive an apocalypse alone? Noah emerges from his two-week fishing trip in the Northwoods of Wisconsin, shocked to learn that a devastating pandemic has swept the world. Should he venture into the fray to find other survivors or retreat into the woods and isolate himself as long as he can? When their paths converge, they face a new struggle ─ learning to trust total strangers as if their very survival depends on it... because it does. Sympatico Syndrome is intent on sparing no one.

So far, they've escaped the virus, but that doesn't mean they've survived the worst pandemic mankind has ever experienced. No longer alone, Ethan, Cassie, and Noah find out that, even together, survival is not assured. Mother Nature has not finished testing them. Ethan knows he's lucky to have found good people, but they're not his family. Awkward, and unsure of his standing, he takes risks to prove he belongs—that he's a useful member of the group. Cassie's children mean everything to her and she will do whatever it takes to see that they not only survive but thrive. Her efforts to create a new normal crash into the realities of a world where nothing can be normal again. Noah balks at being thrust into the role of leader of the group, but he shoulders the responsibility to keep everyone safe. They soon realize that with so many challenges and dangers to face, their group must find a way to survive together or risk being utterly ripped apart.