After the harrowing attack at the precinct, Langford and Jensen continue to follow the tenuous leads they've uncovered, traversing deeper and deeper into the dark underbelly of the Witness cult. But will they find the kidnapped children before Patient Zero strikes again?

After circling around the truth, Langford and Jensen have finally discovered Markoff's trail. The bad news? It leads right into the horrific nightmare world of Patient Zero's psyche.

Having barely survived the journey through Patient Zero's hellscape, Langford and Jensen close in on the location of the kidnapped children. But will the Witnesses make them see the glory of the Empty Man before the agents can come to the rescue?

Final issue! Agents Langford and Jensen finally come face-to-face with the supernatural culprits who kidnapped the Simmons children, while Sister makes a last-ditch attempt to free her brother from the clutches of the sadistic Reverend Markoff.