Claire DeWitt, the world’s best private detective, wakes up one dark night in an ambulance in Oakland: someone has just tried to murder her. But she’s not dead. Not yet. More sure of herself than of the police, Claire follows the clues on a 52-hour odyssey through shimmering Las Vegas and the shabby surrounding desert to find out who wants her dead. But in order to save herself, Claire will have to revisit her own complicated past as she navigates the present: a past of childhood obsessions, rival detectives, lost friends, and mysteries mostly—but not always—solved. Three intertwining stories illuminate three eras of Claire’s life: her early years as an ambitious girl detective in Brooklyn (before it was gentrified), which ended when her best friend and partner in crime-solving disappeared; a case of an unexplained death in the art world of late-1990s Los Angeles, when, devastated by the demise of her mentor in New Orleans, Claire was forced to start again; and her current quest to save her own life from a determined assassin. As the connections between the stories come into focus, the truth becomes clear. But Claire, battered and bruised, will never quit her search for the answer to the biggest mystery of all: how can anyone survive in a world so clearly designed to break our hearts?