Inspired by the life and adventures of his own great-great grandmother, Betty Zane was Zane Grey's first novel and launched his career as a master writer of rousing frontier and Western adventures. Betty Zane is the story of the events culminating in the last battle of the American Revolution, when two hundred Redcoats from British-controlled Detroit along with four hundred Shawnee Indian attacked the small, wood-palisaded Ford Henry on the western frontier. The heroine of the battle—a young, spunky, and beautiful frontier girl—was Betty Zane

As the Revolutionary war draws to an end, the violence on the frontier only accelerates. The infamous Girty brothers incite Indians to a number to massacres, but when the Village of Peace, a Christian utopian settlement is destroyed, the settlers know they will have to hunt him down.

Twilight of a certain summer day, many years ago, shaded softly down over the wild Ohio valley bringing keen anxiety to a traveler on the lonely river trail. He had expected to reach Fort Henry with his party on this night, thus putting a welcome end to the long, rough, hazardous journey through the wilderness; but the swift, on-coming dusk made it imperative to halt.