Typhoid Mary is back in Manhattan and has set her sights on Hell’s Kitchen. With Daredevil preoccupied trying to take down Mayor Fisk, a power vacuum has suddenly formed in Manhattan’s most dangerous neighborhood, and Typhoid Mary aims to fill it with her own unique brand of chaos. But Daredevil isn’t the only guardian watching over the Kitchen’s residents… and SPIDER-MAN is going to prove it!

TYPHOID MARY has returned to Hell’s Kitchen and taken over the neighborhood’s psychiatric hospital, overwhelming Manhattan’s most dangerous neighborhood with her unique telekinetic abilities. When mutants and humans alike get caught in the crossfire, the X-Men have no choice but to intervene… only to square off against THE AMAZING SPIDER-MAN?!