Spider-Man must defend himself on two fronts as Dr. Octopus sets out for revenge and Kraven the Hunter pursues the ultimate prize.

Sam Bullit is running for Mayor of New York City on an anti-Spider-Man campaign, and Daily Bugle Editor-in-Chief J. Jonah Jameson is backing him 100%. But who s pulling Bullit s strings? None other than the Kingpin of Crime. Plus: Spider-Man meets the sexy and elusive cat burglar called the Black Cat, who claws herself into the young web-slinger's life and purrs her way into Peter Parker's. When the Cat gets her paws on a stolen tablet that the Kingpin desperately wants, the crime lord hires the deadly Elektra to retrieve the artifact for him. Collecting: Ultimate Spider-Man 47-53

Collects Ultimate Six #1-7. What happens when Green Goblin, Doctor Octopus, the Sandman, Electro and Kraven the Hunter escape a S.H.I.E.L.D. containment center and join forces? Who will they target as the sixth member of their deadly alliance? Spider-Man must do whatever it takes to stop them, but even with the help of the Ultimates, will that be enough?