When talented young writer Nathan Zuckerman makes his pilgrimage to sit at the feet of his hero, the reclusive master of American Literature, E. I. Lonoff, he soon finds himself enmeshed in the great Jewish writer's domestic life, with all its complexity, artifice and drive for artistic truth. As Nathan sits in breathlessly awkward conversation with his idol, a glimpse of a dark-haired beauty through a closing doorway leaves him reeling. He soon learns that the entrancing vision is Amy Bellette, but her position in the Lonoff household - student? mistress? - remains tantalisingly unclear. Over a disturbed and confusing dinner, Nathan gleans snippets of Amy's haunting Jewish background, and begins to draw his own fantastical conclusions...

Following the wild success of his novel, Carnovsky, Nathan Zuckerman has been catapulted into the literary limelight. As he ventures out onto the streets of Manhattan he finds himself accosted on all sides, the target of admonishers, advisers, would-be literary critics, and – worst of all – fans. An incompetent celebrity, ill at ease with his newfound fame, and unsure of how to live up to his fictional creation’s notoriety, Zuckerman flounders his way through a high-profile affair, the disintegration of his family life, and fends off the attentions of his most tenacious fan yet, as the turbulent decade of the sixties draws to a close around him. But beneath the uneasy glamour are the spectres of the recently murdered Robert Kennedy and Martin Luther King, Jr., and an unsettled Zuckerman feels himself watched…

From the Pulitzer Prize-winning author of American Pastoral—and one of the most renowned writers of the twentieth century—"a ferocious, heartfelt book" (The New Yorker) featuring Nathan Zuckerman whose life is about to unravel when he comes down with a mysterious affliction. Roth has a genius for the comedy of entrapment.... [He] writes America's most raucously funny novels. —Time At forty, the writer Nathan Zuckerman comes down with a mysterious affliction—pure pain, beginning in his neck and shoulders, invading his torso, and taking possession of his spirit. Zuckerman, whose work was his life, is unable to write a line. Now his work is trekking from one doctor to another, but none can find a cause for the pain and nobody can assuage it. Zuckerman himself wonders if the pain can have been caused by his own books. And while he is wondering, his dependence on painkillers grows into an addiction to vodka, marijuana, and Percodan. The Anatomy Lesson is a great comedy of illness written in what the English critic Hermione Lee has described as a manner at once ... brash and thoughtful ... lyrical and wry, which projects through comic expostulations and confessions...a knowing, humane authority. The third volume of the trilogy and epilogue Zuckerman Bound, The Anatomy Lesson provides some of the funniest scenes in all of Roth's fiction as well as some of the fiercest.

In search of the unpublished manuscript of a martyred Yiddish writer, American novelist Nathan Zuckerman travels to Soviet-occupied Prague in the mid-1970s. There, in a nation straightjacketed by totalitarian Communism, he discovers a literary predicament marked by an institutionalised oppression that is rather different from his own. He also discovers, among the subjugated writers with whom he quickly becomes embroiled in a series of bizarre and poignant adventures, an appealingly perverse kind of heroism. The Prague Orgy, consisting of entries from Zuckerman's notebooks recording his sojourn among these outcast artists, completes the trilogy and epilogue Zuckerman Bound. It provides a startling ending to Roth's intricately designed magnum opus on the unforeseen consequences of art.