“Whatever Happened To The Fantastic Four?” It’s the start of a new era for the Fantastic Four...and they’re already in a ton of trouble. Something has gone terribly wrong in New York, and the Thing and Alicia are traveling across America to escape it! But when they stop in a small town for the night and wake up the morning before they arrived, they find themselves caught in a time loop that’s been going on since before they were born...That’s been going on since before they were born...That’s been going on since before they were born...

Reed and Sue are on the run from—well, a lot of things, actually! Things are not going great for the Fantastic Four. They find themselves in even more trouble when they stop in a small town with a terrible secret! That terrible secret is revealed literally on the second page of this issue, and Reed and Sue spend the rest of the issue trying to survive it, but stop reading here if you don’t want it spoiled...Yep, it’s Reed and Sue versus a town full of killer Doombots.

The Human Torch is alone in New York, trying to survive in a city that hates and fears—well, mostly him specifically. There’s just one thing for Johnny to Adopt an all-new secret identity and take an all-new job nobody else wants! But when things at work heat up, Johnny discovers that while you can forget the past, that doesn’t mean it’ll stay buried...and has to decide if there’re certain things that the Human Torch can’t let himself do! Also! In this issue, Johnny Storm fights a tornado!

The Fantastic Four are reunited and all is well...until their convoy is interrupted by NICK SCRATCH and SALEM'S SEVEN! It's an all-out magical BATTLE for SURVIVAL right there on the highway, and the Fantastic Four 100% fail to win it. That's right! This solicit isn't going the way you thought it would! As the truth of what happened is puzzled out, Reed, Sue, Ben, Johnny and Alicia all realize that something more sinister has taken place, and their only hope of undoing it is an impromptu voyage into the unknown...

The Fantastic Four have been restored to their correct dimension and orientation, but they don’t know that some microscopic invaders, immune to all predators on Earth, have come along for the ride! What happens when the Fantastic Four accidentally threaten all life on the planet? Well, they try to fix it. But what happens when they can’t? I’ll tell you what Sue and Johnny team up to pull off their most audacious stunt yet and maybe, just maybe, save us all. Meanwhile, Ben, Alicia and Reed have to convince a skeptical world that what they’re doing is worth Doctor Octopus is in this one! Only for a little bit, because, come on—he’s going up against the FANTASTIC FOUR. It’s gonna be a short fight…. OR IS IT???