To save the woman he loves, the greatest hero of all time becomes the pawn of ultra-dimensional forces when a wounded emissary from a world of doomed super gods comes to Earth on the eve of the Final Crisis. His mission: To recruit Superman's help against an epic, reality-spanning menace that originated in the Crisis on Infinite Earths.

The multiverse-spanning quest for the elixir of the supergods reaches its end on the shores of a battlefield beyond imagination! But first, the Supermen of five worlds must lay bare the darkest secret of the multiverse, expose the shocking origin of the Monitors and come face to face with a seemingly unstoppable evil fuelled by the power of 52 living universes.