How do we conceptualise our psychological, existential and political condition? Anxiety and depression are on the rise in Australia and across the globe; digital media has created a pandemic of loneliness and disconnection; ideological extremism is widening our divisions and threatening our democracies – and all the while, the wellness industry is spinning everything from mindfulness to minimalism into big business. Where does this leave us? Griffith Review 72: States of Mind explores the parameters of our cognitive landscapes and how far they might take us.