Religious texts from The Bible to the Sumerian tablets speak of strange creatures descending from the heavens and mating with humans, their children the superhuman heroes of myth. None of this ever meant anything to Iraq War veteran Hannah Gregory, until she found herself in the crosshairs of a dangerous cult convinced that she's a descendant of these dangerous bloodlines... bloodlines they're determined to eradicate. No Angel is a cosmological and conspiratorial modern western with super powers by way of The Da Vinci Code.

Hannah Gregory finds herself suddenly burdened by the lies her father told in life even as she tries to unravel the truth surrounding his death. Meanwhile, the killer continues his mission to eradicate the Gregory bloodline, all of whom are conveniently gathered in one place for Hannah's father's funeral.

Elliot Cord, the inhuman monster who killed Hannah Gregory's father and brother, has trapped the surviving Gregory family inside their hotel. In order to save the mother she abandoned and the sister she didn't know she had, Hannah will do what she does FIGHT.

Hannah and Jessica leave rural Wisconsin and head to Chicago, where a final battle awaits.