The series begins with Squee in bed praying for his father to be happy, when he notices that his teddy bear, Shmee is not in bed where he should be, he finds him in the closet where two aliens are waiting to abduct Squee for experiments. Another pair of aliens, who are notably more intelligent than the first pair, show up, and the aliens all argue over who should get to take Squee back with them and perform their tests on him, until the second pair tricks the others and take Squee for themselves. Squee later returns home just in time to go to school the next morning. On the way he sees his only friend get attacked by a small dog after his lunch, who proceeds to drag him into his dog house where he is assumed killed. At school, a new kid named Pepito joins the class, and claims to be the antichrist. Pepito is immediately disgusted by everyone in the class except for Squee who he knows feels the same way as him about the others. Pepito violently attacks the other schoolchildren and decimates the school, until the teacher excuses class for the day.

by the creator of Johnny the Homicidal Maniac and the animated Invader Zim

by the creator of Johnny the Homicidal Maniac and the animated Invader Zim

Squee's Wonderful Big Giant Book of Unspeakable Horrors collects together the four issues of the Squee comic book series from SLG Publishing. It also contains reprints from the popular Jhonny the Homicidal Maniac series that didn't appear in the JTHM: Director's Cut book.