America's favorite couple is back! To celebrate its 25th Anniversary, the Eisner Award winning series is back with an ALL NEW story beginning with this #1 issue! Francine and Katchoo are living the dream until they learn a former Parker Girl is in hiding and writing a tell-all book about the wicked empire Darcy Parker built with Katchoo at her side. Determined to stop her, Katchoo enlists the aid of her mercenary sister Tambi and the hunt is on!

Katchoo is on the hunt for a Parker Girl on the run and the trail leads her to Manson, Mass, home of Jet and Rachel (Rachel Rising)! The town is freezing but the trail is red hot when Katchoo faces the cliffhanger of a lifetime!

Jet comes to the rescue when Katchoo meets a man she doesn't like but not before he provides an important clue to finding Katchoo's fugitive Parker Girl.

When Katchoo closes in on her quarry, the rogue Parker Girl Stephanie, she encounters a devastating new challenge... and an unexpected ally.

Katchoo takes a break on a private island and learns that there is much more to the rogue Parker Girl story than she first thought.

Katchoo's secret meeting with Stephanie takes a dangerous turn and Francine makes her mother an offer she can't refuse.

Katchoo takes a leap of faith—literally—to escape a dangerous territory while the threat to Francine and the kids gets too close to home.

Katchoo returns to Manson to deliver Cleopatra's papyrus and meets the women of Rachel Rising! Meanwhile, back at home, Aunt Libby debates a policeman about the bawdy 1970s career of her sister aka Francine's mother!

Katchoo meets Lilith and discovers who is really behind the theft of Cleopatra's Papyrus. Meanwhile the kids set traps around the house to catch the "burglar" who has been watching the house.

Following a stunning revelation, Katchoo heads home to rejoin her family but a dangerous intruder has invaded the house and now holds Aunt Libby and kids hostage. Don't miss this thrilling conclusion of the XXV series!