Dr. Janet Watson and former covert agent Sara Holmes, introduced in the acclaimed A Study in Honor, continue their dangerous investigation into the new American Civil War with the help of fresh allies, advanced technology, and brilliant deduction in this superb reimagining of Sherlock Holmes. It’s been two months since Dr. Janet Watson accepted an offer from Georgetown University Hospital. The training for her new high-tech arm is taking longer than expected, however, leaving her in limbo. Meanwhile, her brilliant friend and compatriot, Sara Holmes, has been placed on leave—punishment for going rogue during their previous adventure. Neither is taking their situation very well. Then an extremist faction called the Brotherhood of Redemption launches an assassination attempt on the president. The attempt fails but causes mass destruction—fifty dead and hundreds more injured, and Holmes takes on the task of investigating the Brotherhood. Holmes is making progress when she abruptly disappears. Watson receives a mysterious message from Holmes’s cousin Micha and learns that her friend has quit the service and is operating in the shadows, investigating clues that link the Brotherhood to Adler Industries. She needs a surgeon, Micha tells Watson. She needs you. Reunited once more, Dr. Watson, Holmes, and Micha embark on a mission through the deep South to clear Holmes’s name, thwart the Brotherhood’s next move, and most important, bring their nemesis to justice for the atrocities she’s committed in the New Civil War.