Non-Alignment is back with a vengeance. In recent years, the number of countries embracing this venerable approach to foreign policy has increased exponentially, making it a force to be reckoned with in world affairs. The war in Ukraine, the expansion of the BRICS group, and the conflict in Gaza have given a special impetus to its rise in a new Active Non-Alignment (ANA). This has gone hand-in-hand with the growing power and influence of the Global South in world politics. In this agenda-setting book, Jorge Heine, Carlos Fortin and Carlos Ominami, explain the origins, dynamics and significance of ANA, for the future of world order. Far from a transitory expression of the current state of affairs, they argue that ANA is here to stay. It provides a powerful guide to action and a fine-tuned compass for the Global Majority, that is, the countries in Africa, Asia and Latin America, to strike out and prioritize their national interests, whilst navigating the perilous waters of a troubled world in the throes of change.