Med student Annabel and her older sister Jezebel are trapped in a waking nightmare. After escaping from the deadly island haunted by the Plague Doctors, the two sisters and fellow survivor, Henry, manage to find salvation on a rickety old boat that promises to take them home. But once again, they encounter the spectral ship that sails the island’s waters, forcing them back to the rocky coast. As they flee the minions of the haunted Spanish Galleon, the old ship’s original manifest provides a clue to the Plague Doctor’s hideous origins. But before they can decipher its meaning, the evil Doctors return with a vengeance. Fighting to stay alive, the three survivors must solve the riddle of the Plague Doctors, and expose the lies and corruption that doomed the island to its supernatural curse. But as they follow the trail of death and horror, they uncover a terrifying new secret. The Plague Doctors are not the only spirits that haunt the island...